BINDING OF DNA TO NATURAL SEPIOLITE: APPLICATIONS IN BIOTECHNOLOGY AND PERSPECTIVES

DNA manipulation is crucial for many biotechnological prospects and medical applications such as gene therapy. This requires the amplification extraction of from bacteria transfer these molecules into cells, including bacterial mammalian cells. The capacity natural magnesium silicate clay mineral sepiolite to bind makes it a potentially useful tool biotechnological/medical strategies. In addition, inexpensive classified non-toxic non-carcinogenic. review will first describe physicochemical interactions between DNA. Then, leverage sepiolite/DNA bacteria, optimize transfection are presented. Finally, putative toxicity its advantages perspectives future prospects, improvement immunotherapy, also discussed.